Incorporating deliverable monitor unit constraints into spot intensity optimization in intensity-modulated proton therapy treatment planning

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Incorporating deliverable monitor unit constraints into spot intensity optimization in IMPT treatment planning

Purpose: This study is to investigate the feasibility and impact of incorporating deliverable monitor unit (MU) constraints into spot intensity optimization in intensity modulated proton therapy (IMPT) treatment planning. Methods: The current treatment planning system (TPS) for IMPT at our institution disregards the deliverable MU constraints in the spot intensity optimization (SIO) routine. It...

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Radiation therapy is a non-invasive treatment modality for cancer patients. Radiation therapy treatment planning for cancer patients provides many challenging optimization problems. Various variables of a treatment plan need to be optimized so that the resulting plan can kill all cancerous cells while minimizing damage on the patient’s normal tissues. Intensity modulated proton therapy (IMPT) h...

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Intensity modulated proton therapy.

Intensity modulated proton therapy (IMPT) implies the electromagnetic spatial control of well-circumscribed "pencil beams" of protons of variable energy and intensity. Proton pencil beams take advantage of the charged-particle Bragg peak-the characteristic peak of dose at the end of range-combined with the modulation of pencil beam variables to create target-local modulations in dose that achie...

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evaluation of treatment planning system monitor unit calculations for three intensity modulated radiotherapy delivery techniques

background: we have validated the monitor unit calculations from a commercially available treatment planning system (tps) for three intensity modulated radiotherapy (imrt) planning techniques for tangential breast irradiation by using ionization chamber measurements. materials and methods: treatment plans were generated for forty-two breast patients by a forward planned field in field technique...

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ژورنال

عنوان ژورنال: Physics in Medicine and Biology

سال: 2013

ISSN: 0031-9155,1361-6560

DOI: 10.1088/0031-9155/58/15/5113